Manchester City defender Nathan Ake was injured only five minutes into the Netherlands’ 1-1 friendly draw with Spain in Amsterdam.
Sergio Canales put Spain ahead but Manchester United midfielder Donny van de Beek volleyed in an equaliser.
Both countries play two more Nations League games this week.
City manager Pep Guardiola, along with his Premier League counterparts at Liverpool and Manchester United, called for a change in scheduling and a return to five substitutions before this international break because of the impact on players.
Liverpool defender Joe Gomez was also injured on Wednesday while training with England for Thursday’s friendly against the Republic of Ireland.
Line-ups
Netherlands
- 13Bizot
- 2HateboerSubstituted forDumfriesat 45′minutes
- 3Veltman
- 4AkéSubstituted forBlindat 6′minutes
- 12Wijndal
- 8WijnaldumSubstituted forKlaassenat 45′minutes
- 21de JongSubstituted forde Vrijat 45′minutes
- 7BerghuisSubstituted forStengsat 45′minutes
- 20van de BeekBooked at 89mins
- 10DepaySubstituted forBabelat 79′minutes
- 19de Jong
Substitutes
- 1Krul
- 5van Aanholt
- 6de Vrij
- 9Babel
- 11Promes
- 14Koopmeiners
- 15Klaassen
- 16Stengs
- 17Blind
- 18Malen
- 22Dumfries
- 23Drommel
Spain
- 23Simón
- 22Bellerín
- 12García
- 4MartínezSubstituted forRamosat 85′minutes
- 14GayàSubstituted forReguilónat 29′minutesBooked at 49mins
- 8Koke
- 16Rodri
- 6CanalesSubstituted forLlorenteat 72′minutes
- 9MorenoSubstituted forTorresat 61′minutes
- 7MorataSubstituted forOlmoat 62′minutesBooked at 84mins
- 10AsensioSubstituted forTraoréat 62′minutes
Substitutes
- 1de Gea
- 2Torres
- 3Reguilón
- 5Busquets
- 11Traoré
- 13Arrizabalaga
- 15Ramos
- 17Ruiz
- 18Torres
- 19Olmo
- 20Roberto
- 21Llorente
Live Text
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Match ends, Netherlands 1, Spain 1.
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Second Half ends, Netherlands 1, Spain 1.
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Corner, Netherlands. Conceded by Koke.
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Attempt blocked. Ryan Babel (Netherlands) right footed shot from outside the box is blocked. Assisted by Donny van de Beek.
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Donny van de Beek (Netherlands) is shown the yellow card for a bad foul.
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Dani Olmo (Spain) wins a free kick in the defensive half.
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Foul by Donny van de Beek (Netherlands).
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Corner, Netherlands. Conceded by Eric García.
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Attempt blocked. Ryan Babel (Netherlands) left footed shot from the centre of the box is blocked. Assisted by Donny van de Beek.
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Foul by Dani Olmo (Spain).
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Denzel Dumfries (Netherlands) wins a free kick in the defensive half.
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Substitution, Spain. Sergio Ramos replaces Íñigo Martínez.
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Dani Olmo (Spain) is shown the yellow card for a bad foul.
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Foul by Dani Olmo (Spain).
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Denzel Dumfries (Netherlands) wins a free kick on the right wing.
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Hand ball by Ryan Babel (Netherlands).
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Attempt missed. Rodrigo (Spain) header from the left side of the six yard box is just a bit too high. Assisted by Dani Olmo with a cross following a corner.
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Corner, Spain. Conceded by Denzel Dumfries.
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Substitution, Netherlands. Ryan Babel replaces Memphis Depay.
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Foul by Ferran Torres (Spain).